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Cajun Grilled Chicken Sauce

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This one’s a keeper! Juicy grilled chicken with Cajun seasoning, done in about 40 mins. Alabama white sauce, tangy and creamy, steals the show. Lighter swap using Greek yogurt. Served it at a cookout, and it flew off the table. Great way to change up grilling season.
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Updated on Wed, 09 Apr 2025 21:09:10 GMT
White plate with grilled chicken breasts and creamy sauce, topped with chopped parsley. Pin it
White plate with grilled chicken breasts and creamy sauce, topped with chopped parsley. | tasteofmoms.com

Down South flavor jumps off the plate with this spicy grilled chicken smothered in cool Alabama white sauce. The fiery Cajun coating forms a tasty crust while the creamy sauce brings perfect balance. Folks always beg me for the scoop on that amazing white sauce whenever I whip this up.

What Makes This So Good

The zesty Cajun seasonings pack the chicken with knockout taste, and that smooth white sauce cools things down just right. You can tweak the spiciness to suit what your family likes. I'm a fan of mixing up the sauce and spices in advance so dinner comes together super quick.

What You Need

Pick up some boneless chicken breasts without skin for perfect grilling. Your Cajun mix combines cayenne, paprika, garlic powder and a little brown sugar that helps make that wonderful dark crust. To whip up that famous Alabama white sauce, grab some mayo, Greek yogurt, apple cider vinegar, and a dash of horseradish for that special zing.

Let's Get Cooking

Coat your chicken well with the Cajun blend and set it aside while you tackle the sauce. Stir together the mayo, yogurt, vinegar and spices, then stick it in the fridge – it'll taste even better as it sits. Heat your grill to medium high and toss on that chicken until you see nice grill lines and it's cooked through. Pour that yummy white sauce over top or let everyone dip as they please.

Make It Your Way

Don't like too much heat? Go easy on the cayenne or add extra if you're after something fiery. Always mix up more sauce than you think you'll need – it disappears fast! Can't grill outdoors? Throw it in a grill pan or pop it in your oven at 400°F and you'll still get awesome results.

Keeping It Fresh

Your chicken will stay tasty in the fridge for about 4 days, and that awesome sauce keeps well for 5 days – just mix it up a bit before you use it. Want to save time? Fix your spice blend and sauce up to 3 days before you plan to cook.

Juicy grilled chicken pieces drizzled with white creamy sauce on a serving plate, with a side bowl of extra dipping sauce and fresh parsley garnish. Pin it
Juicy grilled chicken pieces drizzled with white creamy sauce on a serving plate, with a side bowl of extra dipping sauce and fresh parsley garnish. | tasteofmoms.com

Frequently Asked Questions

→ Why rest the chicken before cooking?
Letting it sit for half an hour helps it cook evenly throughout and enhances the seasoning’s flavor. A small step with big payoff.
→ How can I make it less spicy?
Cut back on the cayenne—try using just half a teaspoon. You can always sprinkle in more later if it needs a kick.
→ How early can I prep the sauce?
Whip it up a day before. The extra time lets the flavors come together nicely. It’ll stay good in the fridge for up to 5 days.
→ What’s the point of pounding the chicken?
It makes the thickness even, so every piece cooks the same. No dry edges or raw spots—just juicy bites all over.
→ Can this be made without dairy?
Yep, swap out the Greek yogurt for a dairy-free version. Problem solved, and it tastes great!

Cajun Grilled Chicken Sauce

Boldly flavored grilled chicken with Cajun seasoning and a creamy, tangy Alabama white sauce. Made lighter with Greek yogurt and fragrant herbs.

Prep Time
40 Minutes
Cook Time
16 Minutes
Total Time
56 Minutes
By: Ashley

Category: Chicken

Difficulty: Intermediate

Cuisine: Southern

Yield: 6 Servings (6 chicken breasts)

Dietary: Low-Carb, Gluten-Free

Ingredients

01 3 tablespoons olive oil.
02 6 pieces of boneless, skinless chicken breast (about 2 pounds).
03 1 tablespoon garlic powder.
04 2 teaspoons dried thyme.
05 1 tablespoon onion powder.
06 2 teaspoons dried oregano.
07 1 teaspoon brown sugar.
08 2 tablespoons sweet paprika.
09 1 teaspoon ground cayenne pepper.
10 1 1/2 teaspoons black pepper.
11 1 1/2 teaspoons kosher salt.
12 1 cup full-fat Greek yogurt.
13 3 tablespoons apple cider vinegar.
14 1/2 cup mayonnaise.
15 2 cloves garlic, minced.
16 1 tablespoon horseradish (prepared).
17 1 tablespoon chopped parsley (fresh).
18 1 tablespoon finely chopped chives (optional).

Instructions

Step 01

If chicken is uneven, gently pound it to make it about 3/4 inch thick. Pat dry.

Step 02

Combine all Cajun seasoning ingredients in a small bowl and stir until everything is mixed well.

Step 03

Pour oil over chicken, making sure it’s coated evenly with the spice blend. Leave it at room temperature for 30 minutes.

Step 04

Blend all the sauce ingredients in a bowl until smooth, then chill in the fridge until ready to serve.

Step 05

Heat grill to 375-400°F and oil the grates. Cook chicken for 6-8 minutes on each side, or until internal temperature hits 165°F.

Step 06

Let the chicken cool for a bit—5 to 10 minutes should do—before enjoying it with the chilled sauce.

Notes

  1. Soaking chicken in brine makes it juicier.
  2. The sauce keeps well if made ahead.
  3. Spice mix stays good up to 3 months.
  4. Works with non-dairy yogurt to skip the dairy.

Tools You'll Need

  • Grill.
  • Thermometer for meat.
  • Bowls for mixing.

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Contains dairy.
  • Eggs are in the mayo.

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 385
  • Total Fat: 22 g
  • Total Carbohydrate: 5 g
  • Protein: 42 g